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Pushing the resolution limit by correcting the Ewald sphere effect in single-particle Cryo-EM reconstructions

The Ewald sphere effect is generally neglected when using the Central Projection Theorem for cryo electron microscopy single-particle reconstructions. This can reduce the resolution of a reconstruction. Here we estimate the attainable resolution and report a “block-based” reconstruction method for e...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhu, Dongjie, Wang, Xiangxi, Fang, Qianglin, Van Etten, James L, Rossmann, Michael G, Rao, Zihe, Zhang, Xinzheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908801/
https://ncbi.nlm.nih.gov/pubmed/29674632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04051-9
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