Lipopolysaccharide-induced maternal inflammation induces direct placental injury without alteration in placental blood flow and induces a secondary fetal intestinal injury that persists into adulthood

PROBLEM: Premature birth complicates 10%–12% of deliveries. Infection and inflammation are the most common etiologies and are associated with increased offspring morbidity and mortality. We hypothesize that lipopolysaccharide (LPS)-induced maternal inflammation causes direct placenta injury and subs...

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Vydáno v:Am J Reprod Immunol
Hlavní autoři: Fricke, Erin M., Elgin, Timothy G., Gong, Huiyu, Reese, Jeff, Gibson-Corley, Katherine N., Weiss, Robert M., Zimmerman, Kathy, Bowdler, Noelle C., Kalantera, Karen M., Mills, David A., Underwood, Mark A., McElroy, Steven J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908742/
https://ncbi.nlm.nih.gov/pubmed/29369434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aji.12816
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