Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy

Geographic atrophy (GA), the late stage of dry age-related macular degeneration is characterized by loss of the retinal pigment epithelial (RPE) layer, which leads to subsequent degeneration of vital retinal structures (e.g., photoreceptors) causing severe vision impairment. Similarly, RPE-loss and...

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Bibliographische Detailangaben
Veröffentlicht in:J Vis Exp
Hauptverfasser: Petrus-Reurer, Sandra, Bartuma, Hammurabi, Aronsson, Monica, Westman, Sofie, Lanner, Fredrik, Kvanta, Anders
Format: Artigo
Sprache:Inglês
Veröffentlicht: MyJove Corporation 2018
Schlagworte:
Cellular Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908677/
https://ncbi.nlm.nih.gov/pubmed/29443034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56702
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