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An in silico model of cytotoxic T-lymphocyte activation in the lymph node following short peptide vaccination
Tumour immunotherapy is dependent upon activation and expansion of tumour-targetting immune cells, known as cytotoxic T-lymphocytes (CTLs). Cancer vaccines developed in the past have had limited success and the mechanisms resulting in failure are not well characterized. To elucidate these mechanisms...
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| Udgivet i: | J R Soc Interface |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5908537/ https://ncbi.nlm.nih.gov/pubmed/29540543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2018.0041 |
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