Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance

Candida glabrata can rapidly acquire mutations that result in drug resistance, especially to azoles and echinocandins. Identification of genetic mutations is essential, as resistance detected in vitro can often be correlated with clinical failure. We examined the feasibility of using whole genome se...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Biswas, Chayanika, Chen, Sharon C-A., Halliday, Catriona, Martinez, Elena, Rockett, Rebecca J., Wang, Qinning, Timms, Verlaine J., Dhakal, Rajat, Sadsad, Rosemarie, Kennedy, Karina J., Playford, Geoffrey, Marriott, Deborah J., Slavin, Monica A., Sorrell, Tania C., Sintchenko, Vitali
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908403/
https://ncbi.nlm.nih.gov/pubmed/29364212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56714
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