Blood free-circulating DNA testing by highly sensitive methylation assay to diagnose colorectal neoplasias

Although methylated TWIST1 is a biomarker of colorectal neoplasia, its detection from serum samples is very difficult by conventional bisulfite-based methylation assays. Therefore, we have developed a new methylation assay that enables counting of even one copy of a methylated gene in a small DNA sa...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Suehiro, Yutaka, Hashimoto, Shinichi, Higaki, Shingo, Fujii, Ikuei, Suzuki, Chieko, Hoshida, Tomomi, Matsumoto, Toshihiko, Yamaoka, Yuko, Takami, Taro, Sakaida, Isao, Yamasaki, Takahiro
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2018
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908299/
https://ncbi.nlm.nih.gov/pubmed/29682198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24768
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