An ADAM-10 dependent EPCR shedding links meningococcal interaction with endothelial cells to purpura fulminans

Purpura fulminans is a deadly complication of Neisseria meningitidis infections due to extensive thrombosis of microvessels. Although a Disseminated Intra-vascular Coagulation syndrome (DIC) is frequently observed during Gram negative sepsis, it is rarely associated with extensive thrombosis like th...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Lécuyer, Hervé, Virion, Zoé, Barnier, Jean-Philippe, Matczak, Soraya, Bourdoulous, Sandrine, Bianchini, Elsa, Saller, François, Borgel, Delphine, Nassif, Xavier, Coureuil, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908201/
https://ncbi.nlm.nih.gov/pubmed/29630665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006981
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