Unique mechanisms of connective tissue growth factor regulation in airway smooth muscle in asthma: Relationship with airway remodelling

Neovascularization, increased basal membrane thickness and increased airway smooth muscle (ASM) bulk are hallmarks of airway remodelling in asthma. In this study, we examined connective tissue growth factor (CTGF) dysregulation in human lung tissue and animal models of allergic airway disease. Immun...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Wang, Junfei, Faiz, Alen, Ge, Qi, Vermeulen, Cornelis J., Van der Velden, Joanne, Snibson, Kenneth J., van de Velde, Rob, Sawant, Sonia, Xenaki, Dikaia, Oliver, Brian, Timens, Wim, ten Hacken, Nick, van den Berge, Maarten, James, Alan, Elliot, John G., Dong, Liang, Burgess, Janette K., Ashton, Anthony W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908101/
https://ncbi.nlm.nih.gov/pubmed/29516637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13576
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