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Structural and functional characterization of the histidine phosphatase domains of human Sts-1 and Sts-2()
The suppressor of T-cell signaling (Sts) proteins, Sts-1 and Sts-2, are homologous phosphatases that negatively regulate signaling pathways downstream of the T-cell receptor. Functional inactivation of Sts-1 and Sts-2 in a murine model leads to resistance to systemic infection by the opportunistic p...
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| Pubblicato in: | Biochemistry |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5907918/ https://ncbi.nlm.nih.gov/pubmed/28759203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00638 |
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