Safety study: is there a pathologic IGF-1, PDGF and TGF-β cytokine expression caused by adjunct BMP-7 in tibial and femoral non-union therapy?

BACKGROUND: In this prospective safety study, we investigated if the characteristic cytokine expression during bone regeneration is manipulated by the local application of bone morphogenetic protein-7 (BMP-7) in non-union surgery. Therefore, the levels of insulin like growth factor 1 (IGF-1), platel...

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Vydáno v:Ther Clin Risk Manag
Hlavní autoři: Fischer, Christian, Reiner, Christian, Schmidmaier, Gerhard, Doll, Julian, Child, Christopher, Grützner, Paul Alfred, Biglari, Bahram, Boxriker, Sonja, Moghaddam, Arash
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907889/
https://ncbi.nlm.nih.gov/pubmed/29713178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S160064
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