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Contribution of TLR4 signaling in intermittent hypoxia-mediated atherosclerosis progression

BACKGROUND: Intermittent hypoxia (IH), a typical character of obstructive sleep apnea (OSA), is related to atherogenesis. However, the role of IH on atherosclerosis (AS) progression and the mechanisms involved remains poorly understood. METHODS: In the present study, high-fat fed ApoE(−/−) mice were...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Zeng, Xianqin, Guo, Rong, Dong, Mei, Zheng, Julia, Lin, Huili, Lu, Huixia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907703/
https://ncbi.nlm.nih.gov/pubmed/29673358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1479-6
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