Molecular Preadaptation to Antimony Resistance in Leishmania donovani on the Indian Subcontinent

Antimonials (Sb) were used for decades for chemotherapy of visceral leishmaniasis (VL). Now abandoned in the Indian subcontinent (ISC) because of Leishmania donovani resistance, this drug offers a unique model for understanding drug resistance dynamics. In a previous phylogenomic study, we found two...

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Publicat a:mSphere
Autors principals: Dumetz, F., Cuypers, B., Imamura, H., Zander, D., D’Haenens, E., Maes, I., Domagalska, M. A., Clos, J., Dujardin, J.-C., De Muylder, G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907651/
https://ncbi.nlm.nih.gov/pubmed/29669889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00548-17
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