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Downregulation of L‐Type Voltage‐Gated Ca(2+), Voltage‐Gated K(+), and Large‐Conductance Ca(2+)‐Activated K(+) Channels in Vascular Myocytes From Salt‐Loading Offspring Rats Exposed to Prenatal Hypoxia

BACKGROUND: Prenatal hypoxia is suggested to be associated with increased risks of hypertension in offspring. This study tested whether prenatal hypoxia resulted in salt‐sensitive offspring and its related mechanisms of vascular ion channel remodeling. METHODS AND RESULTS: Pregnant rats were housed...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Liu, Bailin, Shi, Ruixiu, Li, Xiang, Liu, Yanping, Feng, Xueqin, Chen, Xueyi, Fan, Xiaorong, Zhang, Yingying, Zhang, Wenna, Tang, Jiaqi, Zhou, Xiuwen, Li, Na, Lu, Xiyuan, Xu, Zhice
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907567/
https://ncbi.nlm.nih.gov/pubmed/29545262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.008148
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