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HIPK2-Mediated Transcriptional Control of NMDA Receptor Subunit Expression Regulates Neuronal Survival and Cell Death

NMDA receptors are critical for neuronal communication. Dysfunction in NMDA receptors has been implicated in neuropsychiatric diseases. While it is well recognized that the composition of NMDA receptors undergoes a GluN2B-to-GluN2A switch in early postnatal life, the mechanism regulating this switch...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Shang, Yulei, Zhang, Jiasheng, Huang, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907057/
https://ncbi.nlm.nih.gov/pubmed/29581378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3577-17.2018
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