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Wogonin attenuates nasal polyp formation by inducing eosinophil apoptosis through HIF-1α and survivin suppression

Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) is an inflammatory sinonasal disorder characterized by eosinophilic inflammation and T-helper 2 skewing. Eosinophil accumulation in sinonasal mucosa comprises a major feature of CRSwNP. The study aimed to investigate the effect of the flavone w...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Khalmuratova, Roza, Lee, Mingyu, Mo, Ji-Hun, Jung, YunJae, Park, Jong-Wan, Shin, Hyun-Woo
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906673/
https://ncbi.nlm.nih.gov/pubmed/29670184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24356-5
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