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Inhibition of cyclin-dependent kinase 4 as a potential therapeutic strategy for treatment of synovial sarcoma

Synovial sarcoma is a highly aggressive but rare form of soft tissue malignancy that primarily affects the extremities of the arms or legs, for which current chemotherapeutic agents have not been proven to be very effective. The cyclin-dependent kinase 4/6-retinoblastoma protein (CDK4/6-Rb) pathway...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Principais autores: Li, Xiaoyang, Seebacher, Nicole A., Garbutt, Cassandra, Ma, Hangzhan, Gao, Peng, Xiao, Tao, Hornicek, Francis J., Duan, Zhenfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906661/
https://ncbi.nlm.nih.gov/pubmed/29670090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0474-4
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