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Global H3.3 dynamic deposition defines its bimodal role in cell fate transition

H3.3 is a histone variant, which is deposited on genebodies and regulatory elements, by Hira, marking active transcription. Moreover, H3.3 is deposited on heterochromatin by Atrx/Daxx complex. The exact role of H3.3 in cell fate transition remains elusive. Here, we investigate the dynamic changes in...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Fang, Hai-Tong, EL Farran, Chadi A., Xing, Qiao Rui, Zhang, Li-Feng, Li, Hu, Lim, Bing, Loh, Yuin-Han
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906632/
https://ncbi.nlm.nih.gov/pubmed/29670118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03904-7
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