Modulation of Connexin-36 Gap Junction Channels by Intracellular pH and Magnesium Ions

Connexin-36 (Cx36) protein forms gap junction (GJ) channels in pancreatic beta cells and is also the main Cx isoform forming electrical synapses in the adult mammalian brain. Cx36 GJs can be regulated by intracellular pH (pH(i)) and cytosolic magnesium ion concentration ([Mg(2+)](i)), which can vary...

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Vydáno v:Front Physiol
Hlavní autoři: Rimkute, Lina, Kraujalis, Tadas, Snipas, Mindaugas, Palacios-Prado, Nicolas, Jotautis, Vaidas, Skeberdis, Vytenis A., Bukauskas, Feliksas F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906587/
https://ncbi.nlm.nih.gov/pubmed/29706896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00362
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