Mental Illnesses-Associated Fxr1 and Its Negative Regulator Gsk3β Are Modulators of Anxiety and Glutamatergic Neurotransmission

Genetic variants of the fragile X mental retardation syndrome-related protein 1 (FXR1) have been associated to mood regulation, schizophrenia, and bipolar disorders. Nonetheless, genetic association does not indicate a functional link of a given gene to neuronal activity and associated behaviors. In...

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Udgivet i:Front Mol Neurosci
Main Authors: Khlghatyan, Jivan, Evstratova, Alesya, Chamberland, Simon, Marakhovskaia, Aleksandra, Bahremand, Arash, Toth, Katalin, Beaulieu, Jean-Martin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906571/
https://ncbi.nlm.nih.gov/pubmed/29706865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00119
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