c-Jun-mediated microRNA-302d-3p induces RPE dedifferentiation by targeting p21(Waf1/Cip1)

Dedifferentiation of retinal pigment epithelium (RPE) cells and choroidal neovascularization (CNV) contributes to the pathogenesis of age-related macular degeneration (AMD). MicroRNAs (miRNAs) have crucial roles in AMD onset and progression. We thus aim to investigate the effects of miRNAs on RPE de...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Jiang, Chao, Xie, Ping, Sun, Ruxu, Sun, Xiantao, Liu, Guohua, Ding, Sijia, Zhu, Meidong, Yan, Biao, Liu, Qinghuai, Chen, Xue, Zhao, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906557/
https://ncbi.nlm.nih.gov/pubmed/29670082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0481-5
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