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DNA Damage Inducible Transcript 4 Gene: The Switch of the Metabolism as Potential Target in Cancer

DNA damage inducible transcript 4 (DDIT4) gene is expressed under stress situations turning off the metabolic activity triggered by the mammalian target of rapamycin (mTOR). Several in vitro and in vivo works have demonstrated the ability of DDIT4 to generate resistance to cancer therapy. The link b...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Tirado-Hurtado, Indira, Fajardo, Williams, Pinto, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906527/
https://ncbi.nlm.nih.gov/pubmed/29707520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00106
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