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Random sequences rapidly evolve into de novo promoters
How new functions arise de novo is a fundamental question in evolution. We studied de novo evolution of promoters in Escherichia coli by replacing the lac promoter with various random sequences of the same size (~100 bp) and evolving the cells in the presence of lactose. We find that ~60% of random...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5906472/ https://ncbi.nlm.nih.gov/pubmed/29670097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04026-w |
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