TAp63 contributes to sexual dimorphism in POMC neuron functions and energy homeostasis

Sexual dimorphism exists in energy balance, but the underlying mechanisms remain unclear. Here we show that the female mice have more pro-opiomelanocortin (POMC) neurons in the arcuate nucleus of hypothalamus than males, and female POMC neurons display higher neural activities, compared to male coun...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Wang, Chunmei, He, Yanlin, Xu, Pingwen, Yang, Yongjie, Saito, Kenji, Xia, Yan, Yan, Xiaofeng, Hinton Jr, Antentor, Yan, Chunling, Ding, Hongfang, Yu, Likai, Shu, Gang, Gupta, Rajat, Wu, Qi, Tong, Qingchun, Lagor, William R., Flores, Elsa R., Xu, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906443/
https://ncbi.nlm.nih.gov/pubmed/29670083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03796-7
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