Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation via Hsp90

A salient feature of alcoholic liver disease (ALD) is Kupffer cell (KC) activation and recruitment of inflammatory monocytes/macrophages (Mo/MØ). These key cellular events of ALD pathogenesis may be mediated by extracellular vesicles (EVs). EVs transfer biomaterials, including proteins and miRNAs, a...

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Veröffentlicht in:Hepatology
Hauptverfasser: Saha, Banishree, Momen-Heravi, Fatemeh, Furi, Istvan, Kodys, Karen, Catalano, Donna, Gangopadhyay, Anwesha, Haraszti, Reka, Satishchandran, Abhishek, Iracheta-Vellve, Arvin, Adejumo, Adeyinka, Shaffer, Scott A., Szabo, Gyongyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906190/
https://ncbi.nlm.nih.gov/pubmed/29251792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29732
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