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UPFRONT DPD DEFICIENCY DETECTION TO SECURE 5-FU ADMINISTRATION: PART 2- APPLICATION TO HEAD-AND-NECK CANCER PATIENTS

BACKGROUND: Upfront screening for dihydropyrimidine dehydrogenase (DPD) deficiency in patients scheduled for 5-FU should help reduce the risk of toxicities by preventive adaptive dosing. Our group has developed a simple functional testing categorizing patients upon their DPD status, i.e. extensive m...

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Foilsithe in:Clin Cancer Drugs
Main Authors: Launay, Manon, Ciccolini, Joseph, Fournel, Claire, Blanquicett, Carmelo, Dupuis, Charlotte, Fakhry, Nicolas, Duffaud, Florence, Salas, Sébastien, Lacarelle, Bruno
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906055/
https://ncbi.nlm.nih.gov/pubmed/29682445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2212697x04666170817123425
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