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Data quality of whole genome bisulfite sequencing on Illumina platforms

The powerful HiSeq X sequencers with their patterned flowcell technology and fast turnaround times are instrumental for many large-scale genomic and epigenomic studies. However, assessment of DNA methylation by sodium bisulfite treatment results in sequencing libraries of low diversity, which may im...

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Publicat a:PLoS One
Autors principals: Raine, Amanda, Liljedahl, Ulrika, Nordlund, Jessica
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905984/
https://ncbi.nlm.nih.gov/pubmed/29668744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195972
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