Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS

Reactive astrocytes influence post-injury recovery, repair, and pathogenesis of the mammalian CNS. Much of the regulation of astrocyte reactivity, however, remains to be understood. Using genetic loss and gain-of-function analyses in vivo, we show that the conserved MAP3K13 (also known as leucine zi...

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Vydáno v:Cell Rep
Hlavní autoři: Chen, Meifan, Geoffroy, Cédric G., Meves, Jessica M., Narang, Aarti, Li, Yunbo, Nguyen, Mallorie T., Khai, Vung S., Kong, Xiangmei, Steinke, Christopher L., Carolino, Krislyn I., Elzière, Lucie, Goldberg, Mark P., Jin, Yishi, Zheng, Binhai
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905706/
https://ncbi.nlm.nih.gov/pubmed/29590625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.102
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