Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS

Reactive astrocytes influence post-injury recovery, repair, and pathogenesis of the mammalian CNS. Much of the regulation of astrocyte reactivity, however, remains to be understood. Using genetic loss and gain-of-function analyses in vivo, we show that the conserved MAP3K13 (also known as leucine zi...

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Pubblicato in:Cell Rep
Autori principali: Chen, Meifan, Geoffroy, Cédric G., Meves, Jessica M., Narang, Aarti, Li, Yunbo, Nguyen, Mallorie T., Khai, Vung S., Kong, Xiangmei, Steinke, Christopher L., Carolino, Krislyn I., Elzière, Lucie, Goldberg, Mark P., Jin, Yishi, Zheng, Binhai
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905706/
https://ncbi.nlm.nih.gov/pubmed/29590625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.102
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