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Immune Checkpoint Targeting in Cancer Therapy: Towards Combination Strategies with Curative Potential

Research in two fronts has enabled the development of therapies that provide significant benefit to cancer patients. One area stems from a detailed knowledge of mutations that activate or inactivate signaling pathways that drive cancer development. This work triggered the development of targeted the...

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Detalles Bibliográficos
Publicado en:Cell
Main Authors: Sharma, Padmanee, Allison, James P.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905674/
https://ncbi.nlm.nih.gov/pubmed/25860605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.03.030
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