The synaptotagmin C2B domain calcium-binding loops modulate the rate of fusion pore expansion

In chromaffin cells, the kinetics of fusion pore expansion vary depending on which synaptotagmin isoform (Syt-1 or Syt-7) drives release. Our recent studies have shown that fusion pores of granules harboring Syt-1 expand more rapidly than those harboring Syt-7. Here we sought to define the structura...

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Gepubliceerd in:Mol Biol Cell
Hoofdauteurs: Bendahmane, Mounir, Bohannon, Kevin P., Bradberry, Mazdak M., Rao, Tejeshwar C., Schmidtke, Michael W., Abbineni, Prabhodh S., Chon, Nara L., Tran, Sherleen, Lin, Hai, Chapman, Edwin R., Knight, Jefferson D., Anantharam, Arun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905296/
https://ncbi.nlm.nih.gov/pubmed/29444959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-11-0623
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