Inhibition of Systemic Hyaluronan Synthesis Exacerbates Murine Hepatic Carcinogenesis

Background/Aim: Hyaluronan (HA) is used as a biomarker of liver fibrosis, which is a key risk factor for the development of hepatocellular carcinoma (HCC). We examined the effects of prolonged pharmacological inhibition of HA synthesis on liver carcinogenesis. Materials and Methods: Liver tumors wer...

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Gepubliceerd in:In Vivo
Hoofdauteurs: MIKAMI, KENICHIRO, ENDO, TETSU, SAWADA, NAOYA, IGARASHI, GO, KIMURA, MASAYO, SAKURABA, HIROTAKE, FUKUDA, SHINSAKU
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: International Institute of Anticancer Research 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905194/
https://ncbi.nlm.nih.gov/pubmed/29475909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.11234
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