TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus

We recently reported the discovery of a new parasite-derived protein that functionally mimics the immunosuppressive cytokine transforming growth factor (TGF)-β. The Heligmosomoides polygyrus TGF-β Mimic (Hp-TGM) shares no homology to any TGF-β family member, however it binds the mammalian TGF-β rece...

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Detalhes bibliográficos
Publicado no:Int J Parasitol
Main Authors: Smyth, Danielle J., Harcus, Yvonne, White, Madeleine P.J., Gregory, William F., Nahler, Janina, Stephens, Ian, Toke-Bjolgerud, Edward, Hewitson, James P., Ivens, Alasdair, McSorley, Henry J., Maizels, Rick M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904571/
https://ncbi.nlm.nih.gov/pubmed/29510118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpara.2017.12.004
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