Root Extract of Polygonum cuspidatum Siebold & Zucc. Ameliorates DSS-Induced Ulcerative Colitis by Affecting NF-kappaB Signaling Pathway in a Mouse Model via Synergistic Effects of Polydatin, Resveratrol, and Emodin

Background: Polygonum cuspidatum Siebold & Zucc. (PCS) has antibacterial properties and may prevent Ulcerative colitis (UC) but related molecular mechanism remains unknown. NF-κB signaling pathway is associated with inflammatory responses and its inactivation may be critical for effective therap...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Liu, Baohai, Li, Shuangdi, Sui, Xiaodan, Guo, Lianyi, Liu, Xingmei, Li, Hongmei, Gao, Leming, Cai, Shusheng, Li, Yanrong, Wang, Tingting, Piao, Xuehua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904535/
https://ncbi.nlm.nih.gov/pubmed/29695964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00347
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