Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes

L-ascorbic acid (Vitamin C) can enhance the meiotic maturation and developmental competence of porcine oocytes, but the underlying molecular mechanism remains obscure. Here we show the role of ascorbic acid in regulating epigenetic status of both nucleic acids and chromatin to promote oocyte maturat...

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Foilsithe in:Sci Rep
Main Authors: Yu, Xiao-Xia, Liu, Yun-Hua, Liu, Xiao-Man, Wang, Pei-Chao, Liu, Shuai, Miao, Jia-Kun, Du, Zhi-Qiang, Yang, Cai-Xia
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904140/
https://ncbi.nlm.nih.gov/pubmed/29666467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24395-y
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