Extracellular Hsp70 induces inflammation and modulates LPS/LTA-stimulated inflammatory response in THP-1 cells

Extracellular Hsp70 (eHsp70) can act as damage-associated molecular pattern (DAMP) via Toll-like receptors TLR2 and TLR4, and stimulate immune and inflammatory responses leading to sterile inflammation and propagation of already existing inflammation. It was found elevated in the blood of patients w...

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Publicado en:Cell Stress Chaperones
Main Authors: Hulina, Andrea, Grdić Rajković, Marija, Jakšić Despot, Daniela, Jelić, Dubravko, Dojder, Ana, Čepelak, Ivana, Rumora, Lada
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2017
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Original Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904080/
https://ncbi.nlm.nih.gov/pubmed/29067554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0847-0
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