Outside-in HLA class I signaling regulates ICAM-1 clustering and endothelial-monocyte interactions via mTOR in transplant antibody-mediated rejection

Antibody-mediated rejection (AMR) resulting in transplant allograft vasculopathy (TAV) is the major obstacle for long-term survival of solid organ transplants. AMR is caused by donor-specific antibodies to HLA which contribute to TAV by initiating outside-in signaling transduction pathways that elic...

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Vydáno v:Am J Transplant
Hlavní autoři: Salehi, Sahar, Sosa, Rebecca A., Jin, Yi-Ping, Kageyama, Shoichi, Fishbein, Michael C., Rozengurt, Enrique, Kupiec-Weglinski, Jerzy W., Reed, Elaine F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904014/
https://ncbi.nlm.nih.gov/pubmed/29045076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.14544
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