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Variant pathogenicity evaluation in the community-driven Inherited Neuropathy Variant Browser

Charcot-Marie-Tooth disease (CMT) is an umbrella term for inherited neuropathies affecting an estimated 1 in 2500 people. Over 120 CMT and related genes have been identified and clinical gene panels often contain more than 100 genes. Such a large genomic space will invariantly yield variants of unce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Mutat
Hauptverfasser: Saghira, Cima, Bis, Dana M., Stanek, David, Strickland, Alleene, Herrmann, David N., Reilly, Mary M., Scherer, Steven S., Shy, Mike, Züchner, Stephan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903998/
https://ncbi.nlm.nih.gov/pubmed/29473246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23412
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