Enhancement of Alpha 1-antitrypsin Production in Pichia pastoris by Designing and Optimizing Medium Using Elemental Analysis

Background: Human alpha 1-antitrypsin (AAT) is a monomeric glycosylated protein; it is the potent inhibitor of a whole range of serine proteases and protects tissues against their destructive effects. The human plasma-derived AAT, which is currently used to augment the AAT level in patients, is limi...

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Bibliographic Details
Published in:Iran J Biotechnol
Main Authors: Tavasoli, Tina, Arjmand, Sareh, Ranaei Siadat, Seyed Omid, Shojaosadati, Seyed Abbas, Sahebghadam Lotfi, Abbas
Format: Artigo
Language:Inglês
Published: National Institute of Genetic Engineering and Biotechnology 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903909/
https://ncbi.nlm.nih.gov/pubmed/29845074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/ijb.1808
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