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An incoherent feedforward loop facilitates adaptive tuning of gene expression
We studied adaptive evolution of gene expression using long-term experimental evolution of Saccharomyces cerevisiae in ammonium-limited chemostats. We found repeated selection for non-synonymous variation in the DNA binding domain of the transcriptional activator, GAT1, which functions with the repr...
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| Publicado en: | eLife |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5903863/ https://ncbi.nlm.nih.gov/pubmed/29620523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32323 |
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