A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans

How multicellular organisms respond to and are impacted by severe hypothermic stress is largely unknown. From C. elegans screens for mutants abnormally responding to cold-warming stimuli, we identify a molecular genetic pathway comprising ISY-1, a conserved uncharacterized protein, and ZIP-10, a bZI...

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Pubblicato in:eLife
Autori principali: Jiang, Wei, Wei, Yuehua, Long, Yong, Owen, Arthur, Wang, Bingying, Wu, Xuebing, Luo, Shuo, Dang, Yongjun, Ma, Dengke K
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2018
Soggetti:
Chromosomes and Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903861/
https://ncbi.nlm.nih.gov/pubmed/29664006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35037
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