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VEGF-C promotes the development of lymphatics in bone and bone loss
Patients with Gorham-Stout disease (GSD) have lymphatic vessels in their bones and their bones gradually disappear. Here, we report that mice that overexpress VEGF-C in bone exhibit a phenotype that resembles GSD. To drive VEGF-C expression in bone, we generated Osx-tTA;TetO-Vegfc double-transgenic...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5903859/ https://ncbi.nlm.nih.gov/pubmed/29620526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.34323 |
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