Presence of novel triple mutations in the pvdhfr from Plasmodium vivax in Mangaluru city area in the southwestern coastal region of India

BACKGROUND: Genes encoding dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) are the targets of sulfadoxine–pyrimethamine (SP) present in artemisinin based combination therapy (ACT; artesunate + sulfadoxine pyrimethamine) for Plasmodium falciparum. Although SP is generally not used...

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Vydáno v:Malar J
Hlavní autoři: Joy, Shiny, Ghosh, Susanta K., Achur, Rajeshwara N., Gowda, D. Channe, Surolia, Namita
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902849/
https://ncbi.nlm.nih.gov/pubmed/29661235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2316-3
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