Characterization of AiiK, an AHL lactonase, from Kurthia huakui LAM0618(T) and its application in quorum quenching on Pseudomonas aeruginosa PAO1

N-Acyl homoserine lactones (AHLs) act as the key quorum sensing (QS) signal molecules in gram-negative bacteria, which coordinates gene expression and then activates various processes, including biofilm formation and production of virulence factors in some pathogens. Quorum quenching (QQ), which is...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Dong, Weiwei, Zhu, Jie, Guo, Xiang, Kong, Delong, Zhang, Qi, Zhou, Yiqing, Liu, Xiaoyang, Zhao, Shumiao, Ruan, Zhiyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902575/
https://ncbi.nlm.nih.gov/pubmed/29662232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24507-8
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