Interleukin-15-Cultured Dendritic Cells Enhance Anti-Tumor Gamma Delta T Cell Functions through IL-15 Secretion

Dendritic cell (DC) vaccination can be an effective post-remission therapy for acute myeloid leukemia (AML). Yet, current DC vaccines do not encompass the ideal stimulatory triggers for innate gamma delta (γδ) T cell anti-tumor activity. Promoting type 1 cytotoxic γδ T cells in patients with AML is,...

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Publicat a:Front Immunol
Autors principals: Van Acker, Heleen H., Anguille, Sébastien, De Reu, Hans, Berneman, Zwi N., Smits, Evelien L., Van Tendeloo, Viggo F.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902500/
https://ncbi.nlm.nih.gov/pubmed/29692776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00658
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