In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design

Plants are extensively used in traditional medicine, and several plant antimicrobial peptides have been described as potential alternatives to conventional antibiotics. However, after more than four decades of research no plant antimicrobial peptide is currently used for treating bacterial infection...

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Publicat a:Nat Commun
Autors principals: Porto, William F., Irazazabal, Luz, Alves, Eliane S. F., Ribeiro, Suzana M., Matos, Carolina O., Pires, Állan S., Fensterseifer, Isabel C. M., Miranda, Vivian J., Haney, Evan F., Humblot, Vincent, Torres, Marcelo D. T., Hancock, Robert E. W., Liao, Luciano M., Ladram, Ali, Lu, Timothy K., de la Fuente-Nunez, Cesar, Franco, Octavio L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902452/
https://ncbi.nlm.nih.gov/pubmed/29662055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03746-3
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