Identification of a novel metabolic-related mutation (IDH1) in metastatic pancreatic cancer

Isocitrate dehydrogenase 1 (IDH1) is a metabolic enzyme implicated in cancer cell metabolic reprogramming. This is underscored by the detection of functional, somatic IDH1 mutations frequently found in secondary glioblastoma. To our knowledge, there has never been a reported, validated case of an ID...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Biol Ther
Prif Awduron: Brody, Jonathan R., Yabar, Cinthya S., Zarei, Mahsa, Bender, Joseph, Matrisian, Lynn M., Rahib, Lola, Heartwell, Craig, Mason, Kimberly, Yeo, Charles J., Peiper, Stephen C., Jiang, Wei, Varieur, Katelyn, Madhavan, Subha, Petricoin, Emanuel, Fortuna, Danielle, Curtis, Mark, Wang, Zi-Xuan, Pishvaian, Michael J., Winter, Jordan M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2018
Pynciau:
Bedside to Bench Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902240/
https://ncbi.nlm.nih.gov/pubmed/27466707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1210743
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