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E2F/DP prevents cell cycle progression in endocycling fatbody cells by suppressing dATM expression

To understand the consequences of the complete elimination of E2F regulation we profiled the proteome of Drosophila dDP mutants that lack functional E2F/DP complexes. The results uncovered changes in the larval fatbody, a differentiated tissue that grows via endocycles. We report an unexpected mecha...

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Библиографические подробности
Опубликовано в: :Dev Cell
Главные авторы: Guarner, Ana, Morris, Robert, Korenjak, Michael, Boukhali, Myriam, Zappia, Maria Paula, Van Rechem, Capucine, Whetstine, Johnathan R., Ramaswamy, Sridhar, Zou, Lee, Frolov, Maxim V., Haas, Wilhelm, Dyson, Nicholas J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901703/
https://ncbi.nlm.nih.gov/pubmed/29233476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.11.008
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