E2F/DP prevents cell cycle progression in endocycling fatbody cells by suppressing dATM expression

To understand the consequences of the complete elimination of E2F regulation we profiled the proteome of Drosophila dDP mutants that lack functional E2F/DP complexes. The results uncovered changes in the larval fatbody, a differentiated tissue that grows via endocycles. We report an unexpected mecha...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Guarner, Ana, Morris, Robert, Korenjak, Michael, Boukhali, Myriam, Zappia, Maria Paula, Van Rechem, Capucine, Whetstine, Johnathan R., Ramaswamy, Sridhar, Zou, Lee, Frolov, Maxim V., Haas, Wilhelm, Dyson, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901703/
https://ncbi.nlm.nih.gov/pubmed/29233476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.11.008
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