E2F/DP prevents cell cycle progression in endocycling fatbody cells by suppressing dATM expression

To understand the consequences of the complete elimination of E2F regulation we profiled the proteome of Drosophila dDP mutants that lack functional E2F/DP complexes. The results uncovered changes in the larval fatbody, a differentiated tissue that grows via endocycles. We report an unexpected mecha...

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Publicado en:Dev Cell
Autores principales: Guarner, Ana, Morris, Robert, Korenjak, Michael, Boukhali, Myriam, Zappia, Maria Paula, Van Rechem, Capucine, Whetstine, Johnathan R., Ramaswamy, Sridhar, Zou, Lee, Frolov, Maxim V., Haas, Wilhelm, Dyson, Nicholas J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901703/
https://ncbi.nlm.nih.gov/pubmed/29233476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.11.008
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