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The effect of the first-generation HCV-protease inhibitors boceprevir and telaprevir and the relation to baseline NS3 resistance mutations in genotype 1: experience from a small Swedish cohort

BACKGROUND: The clinical experience with protease-inhibitor (PI) triple regimen appears disappointing regarding effect, side effects, high work load, and costs. This real-world study evaluates baseline and emerging resistance-associated substitutions (RASs) and their significance for treatment outco...

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Detalhes bibliográficos
Publicado no:Ups J Med Sci
Main Authors: Kjellin, Midori, Wesslén, Terése, Löfblad, Erik, Lennerstrand, Johan, Lannergård, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901468/
https://ncbi.nlm.nih.gov/pubmed/29536805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03009734.2018.1441928
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