MiR-130a is aberrantly overexpressed in adult acute myeloid leukemia with t(8;21) and its suppression induces AML cell death

BACKGROUND: Emerging evidence has revealed that miRNAs can function as oncogenes or tumor suppressor genes in leukemia. The ectopic expression of miR-130a has been reported in chronic leukemia, but our understanding of the biological implications of miR-130a expression remains incomplete. METHODS: W...

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Veröffentlicht in:Ups J Med Sci
Hauptverfasser: Ding, Chao, Chen, Su-Ning, Macleod, Roderick A. F., Drexler, Hans G., Nagel, Stefan, Wu, De-Pei, Sun, Ai-Ning, Dai, Hai-Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901465/
https://ncbi.nlm.nih.gov/pubmed/29493383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03009734.2018.1440037
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