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Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet–induced systemic inflammation, microglial activation, and reduced neuroplasticity

The goal of this study was to identify the intrinsic links that explain the effect of a Western diet (WD) on cognitive dysfunction. Specific pathogen-free, wild-type mice were fed either a control diet (CD) or a high-fat, high-sucrose WD after weaning and were euthanized at 10 mo of age to study the...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Jena, Prasant Kumar, Sheng, Lili, Di Lucente, Jacopo, Jin, Lee-Way, Maezawa, Izumi, Wan, Yu-Jui Yvonne
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901391/
https://ncbi.nlm.nih.gov/pubmed/29401580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700984RR
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