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IL-21-secreting hUCMSCs combined with miR-200c inhibit tumor growth and metastasis via repression of Wnt/β-catenin signaling and epithelial–mesenchymal transition in epithelial ovarian cancer

BACKGROUND: Epithelial ovarian cancer (EOC) with insidious characteristic manifests no symptoms in its early onset but most patients have advanced and distant cancer metastasis at diagnosis. Innovative early diagnosis and effective treatment of EOC are urgently needed. METHODS: In the study, we deve...

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Publicat a:Onco Targets Ther
Autors principals: Zhang, Yunxia, Wang, Jing, Wu, Di, Li, Miao, Zhao, Fenshu, Ren, Mulan, Cai, Yunlong, Dou, Jun
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901132/
https://ncbi.nlm.nih.gov/pubmed/29692616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S147855
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