IL-21-secreting hUCMSCs combined with miR-200c inhibit tumor growth and metastasis via repression of Wnt/β-catenin signaling and epithelial–mesenchymal transition in epithelial ovarian cancer

BACKGROUND: Epithelial ovarian cancer (EOC) with insidious characteristic manifests no symptoms in its early onset but most patients have advanced and distant cancer metastasis at diagnosis. Innovative early diagnosis and effective treatment of EOC are urgently needed. METHODS: In the study, we deve...

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Bibliografiska uppgifter
I publikationen:Onco Targets Ther
Huvudupphovsmän: Zhang, Yunxia, Wang, Jing, Wu, Di, Li, Miao, Zhao, Fenshu, Ren, Mulan, Cai, Yunlong, Dou, Jun
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove Medical Press 2018
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901132/
https://ncbi.nlm.nih.gov/pubmed/29692616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S147855
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